What Is Sodium Hyaluronate?

Check your current moisturizers and cosmetics. If they do not contain sodium hyaluronate, you’re missing the absolute basic to getting great skin. Your skin is the largest organ in the human body [18]. It is your job to protect it and keep it healthy, but life gets busy, we kill our plants, and forget to hydrate. Sodium hyaluronate is an age old beuaty industry secret to ageless skin and its time you start you using it.

Sodium hyaluronate is a salt derivative of our bodies natural supply of hyaluronic acid, the primary powerhouse molecule responsible for preserving our skins water-based moisture. It is the most essential hydrating ingredient for moisturizers, serums, and cleansers.

And what does it do? Sodium hyaluronate can be summed up in three ways…


  • Hydration
  • Volume
  • Elasticity


Sodium hyaluronate (SA) is a hygroscopic, glycosaminoglycan, humectant, salt! Why are these things important? because, we are here to tell you why you need to add sodium hyaluronate to your skincare routine today. Its not a question of should, but of must! 

Sodium Hyaluronate Is Hygroscopic:

A hygroscopic (high-grow-scope-ic) substance absorbs water from its surroundings. Sodium hyaluronate is a hygroscopic substance, meaning it has a strong affinity for water. [1]. It will hydrate the skin thoroughly. 

Sodium Hyaluronate Is A Humectant:

Sodium hyaluronate is a humectant (hue-mec-tant). Humectants are one of three moisturizer categories. They are special hydration ingredients that attract moisture from their environment for softer, clearer skin [2]. 

Sodium Hyaluronate Is A Glycosaminoglycan (GAG):

Hyaluronic acid (HA) is one of several glycosaminoglycans (gly-cosa-ming-licans) or GAG. A GAG’s main purpose is cell hydration.  Hyaluronic acid is a special glycosaminoglycan that not only binds water molecules, but also retains them. Compared to other GAG’s, HA has the simplest structure, but is a rather large molecule. Sodium hyaluronate is its salt derivative and is even more simple than its parent in size and structure [3].

Sodium Hyaluronate Is A Salt:

Sodium hyaluronate is a very small salt that loves water! It captures water and keeps it from leaving our skin. Salts are typically hygroscopic substances [4]. 

quick sodium hyaluronate facts

What Are The Benefits of Sodium Hyaluronate?

Resupplies Water Based Moisture

Your hyaluronic acid levels decrease with time. As your supply goes down, your skin will start to lose its softness, elasticity, and overall moisture. Sodium hyaluronate draws hydration back into the skin and resupplies the lost HA levels. 

Cleanses For Clearer Skin

People normally have a difficult time maintaining clear skin. Any little thing, bacteria, stress, excess oil production, trigger foods (chocolate and greasy foods), or dead skin cells can cause breakouts without a warning [11]. SH hydrates the skin. Water clears skin. Sodium hyaluronate is a trick up the sleeve for clear skin.

Firms And Tightens

Hyaluronic acid is most consistent in the skin. This means it contributes to maintaining your skin elasticity. Your skin’s tightness or firmness can eventually become lose and saggy with age. Sodium hyaluronate can bring back your skin’s shape. 

Combats Early Signs of Aging

The number one thing sodium hyaluronate is known for is its hydrating effects. Hydration is the key to good aging. Drink lots of water and use the benefits of SH. 

Hydrates Dry Skin

It’s a given, sodium hyaluronate hydrates. It is a water loving salt that protects your bodies water levels, preventing water from escaping while attracting more water for less dryness.

Reduces Wrinkles

Sodium hyaluronate adds texture to the skin through hydration. By filling your skin with the water it needs, plumping results for a balanced complexion. Plump is actually how you want your skin to be. Plumpness reduces sagginess, fine lines, tiredness, and wrinkles because they are filled in. 

benefits of sodium hyaluronate

What Is Hyaluronic Acid?

Your skin is day in and day out losing water and moisture. Our bodies are 60% water. Retention for this level gradually declines with age, which explains why our skin gets wrinkles and dry over time [7]. 

A source of much of our skin’s moisture retention is through something many dermatologists and cosmetologists are familiar with, hyaluronic acid (HA). 

In terms of chemistry, an acid is a substance that promotes certain chemical reactions. While it has acid in the name, hyaluronic acid is actually a natural carbohydrate found in our bodies. It is a clear fluid that surrounds our bodies joints for lubrication and is our skins main strength for moisture. It regulates our bodies water-based moisture and stabilizes the skin.

We have an abundant supply of hyaluronic acid in our eyes, between our tissues, and beneath our skin, primarily in the dermis layer [8].

When Was Hyaluronic Acid First Discovered?

First discovered in the vitreous body of a cow’s eyes, hyaluronan was first isolated by Karl Meyer and his colleague John Palmer in 1934. Hyaluronic acid contains two sugar molecules, one of which is uronic acid. They appropriately named this newly discovered molecule hyaluronic acid [5].

How Is Sodium Hyaluronate Made?

The chemical structure of hyaluronan was broken down by Karl Mayer and his colleagues. Isolated first as an acid, but under physiological conditions it became a salt (sodium hyaluronate). It was first clinically applied for humans as a vitreous substitution during eye surgery in the 1950’s [6].

What Is Sodium Hyaluronate Used For?

Sodium hyaluronate has a medicinal side and cosmetic side. Sodium hyaluronate has many uses both in the medical field and the health and beauty industry. From surgeries to injections, this little molecule sure makes its way through. 

The Cosmetic Side of Sodium Hyaluronate

The singular beauty of SA is its anti-aging abilities. It draws moisture from its surroundings while blocking any water-based moisture from escaping. Sodium hyaluronate improves firmness, hydrates, smooths fine lines, plumps the skin, and resupplies our bodies natural supply of hyaluronic acid. 

The Medicinal Side of Sodium Hyaluronate

In the medicinal sense, because sodium hyaluronate is part of our bodies surrounding joint fluids and acts like a shock absorber and lubricant, it is used often in the medical field to treat knee pain caused by osteoarthritis via injection [9].

Osteoarthritis: a long term condition where cartilage between joints wear away, forcing bones to rub against each other [10].

Sodium Hyaluronate vs Hyaluronic Acid

Sodium hyaluronate or hyaluronan is an already present fluid within the human body. Sodium hyaluronate is the synthetic salt derivative of hyaluronan. One is a fluid, the other is a salt. You typically will see sodium hyaluronate within ingredient facts in skincare products. 

The size between the two molecules also are significantly different. Hyaluronan is a large molecule that has a hard time penetrating through skin layers, sodium hyaluronate on the other hand is a very small molecule, which can pass through all skin layers with ease.

Why Your Skin Needs Sodium Hyaluronate 

It doesn’t matter if you have either dry skin or oily skin, sodium hyaluronate is something all skin types are crying out for. Just like blondies wish to be brunettes, dry skin types are jealous of the oily skin people and visa versa, but let’s not fight here, both skin types can find common ground and balance in sodium hyaluronate.

We all have a skin type. Do you know your skin type? For clarification, let’s talk about you, your skin, and sodium hyaluronate.

What Is Dehydrated Skin?

We all know what dehydration means, but how about dehydrated skin? Dehydrated skin is not the same as dry skin. 

It is not even a skin type, but a condition[20]. Your probably think “Great, now I have a condition.” No, you are fine, but you can do better. Dehydrated skin simply means your skin is parched. It lacks water. External factors like a dry environment, not drinking enough water, your diet, or caffeine all could all dehydrate your skin over time. Internal factors, like your bodies natural supply of hyaluronic acid may be lacking and causing dehydration too. Your skin has become like those plants in your house that have been forgotten. 

asian woman in front of plants with a cup of coffee

Humans are like plants, they can get dehydrated too

So what does dehydrated skin feel/look like? 

  • Appears dull
  • Excessive oil
  • Dark areas may appear
  • Lacks radiance
  • Tight skin
  • Redness

Is There A Solution?

Dehydrated skin is nothing to fear or be worried about. You recognize what is wrong, and now you can take a step further and find a solution. 

If it is something that bothers you, talk with your dermatologist on possible solutions. Sodium hyaluronate will no doubt be on their list of possible solutions. This is because your body may be lacking hyaluronic acid. 

To resupply your HA, use products that contain sodium hyaluronate as they draw moisture back into your skin. Serums are the best product choice, as most will likely contain this important salt.

What Is Dry Skin Then?

Dry skin is when you lack natural oils, not water. 

What does dry skin feel/look like?

  • Flaky
  • Uncomfortable
  • Itchy

Dry skin lacks oils, specifically sebum. Attention on oil production is more the focus when  it comes to dry skin. Apply oil based products for dry skin [19]. Sodium hyaluronate is an all skin type ingredient that will restore lost water, stop signs of aging, and reduce wrinkles. Age with purpose.

How Do I Use Sodium Hyaluronate?

Remember how SH is hygroscopic? This means it will attract water without any effort for deep skin hydration. Because of this, you should use your sodium hyaluronate serums or other products after washing your face or taking a shower when your skin is the most wet. 

What Skin Types Do Sodium Hyaluronate Work Well With?

Sodium hyaluronate is a salt derivative of hyaluronic acid. Because this acid is consistent throughout the human body, allergic reactions, rashes, itchiness, or other skin sensitivity is likely not to occur.  Sodium hyaluronate is generally safe for all skin types. 

How Much Sodium Hyaluronate Should Be In A Skincare Product?

Sodium hyaluronate is a very small molecule that easily slips past the bodies skin layers for moisture. Because it is so small, a very minuscule amount is needed for best results. Less is more when it comes this amazing additive. Most products normally include just 1% SA.

Is Sodium Hyaluronate Anti-Aging?

What happens to your skin as you age? Age is a natural part of life and our skin slowly loses its structure, stability, and moisture retention with age. Hydration is the key to good aging. 

hydration is the key to good aging

Do you remember what hyaluronic acid does? It regulates water balance and stabilizes the skin. If you ever watched the 1996 TV series, The Magic School Bus, season two, episode six, Wet All Over, you would know that the water cycle is a never ending process by heart. Not only does the earth lose its water, but us too. 

The Anti-Aging Characteristics of SA

Sodium hyaluronate is one of several humectants. Humectants are a group of familiar beauty industry hydration ingredients. They are water retaining molecules, meaning they essentially prevent water from evaporating. The more water that is retained within your body, the more soft and youthful it will be. 

Not one skincare ingredient or group, even humectants, can completely prevent water from evaporating and drying out the skin, but they do block a significant amount of it [12]. Humectants like sodium hyaluronate have a very anti-aging characteristic to them because of their water retaining properties. 

Signs of Aging And How Sodium Hyaluronate Can Help

Still, in addition to incorporating sodium hyaluronate into your skincare routine, there are several other improvements an individual can utilize for a healthy complexion. Is there a key to good aging? Simple habits can make the difference between good and bad aging.

What you can do to keep a young and healthy complexion:

  • Utilize the benefits of sodium hyaluronate. Develop a sound skincare routine that incorporates a sodium hyaluronate.
  • Apply sunscreen. Applying sunscreen may be considered more of a summer thing, however 80% of facial skin aging is due to UV radiation and should be used in all seasons. 
  • Take cold showers. Although cold showers aren’t everybody’s forte, they do promote good circulation. Cold showers are an age old remedy for sensitive skin.
  • Take fewer hot showers. Decompressing in a hot shower is one of life’s pleasures, but they also are a killer skin dehydrator. Switch back and forth between hot and cold showers [13].
  • Don’t smoke. It may not go without saying, smoking hurts not only the lungs, but also can add to damaged skin and more wrinkles. Smoke less for healthy skin [14]. 
  • Drink water! The  U.S. National Academies of Sciences, Engineering, and Medicine recommend that women drink an average of 11.5 cups of water per day, while men drink 15.5 cups a day. Many foods contribute to your water intake. Stay hydrated. Drinking water clears that skin [15]!  
  • Consider A Humidifier. If you were a plant, what plant would you be? Plants love humidity! Just like plants, your skin like moisture. Consider investing in a humidifier to give your plants and skin some love!

You may have the brightest, healthiest skin, but age is a complex biological process and slowly, but surely your skin will change. 

Natural characteristics of aging skin includes:

  • Loss of elasticity. Your skin will lose elasticity causing it to be looser.
  • Skin tags: wrinkles and dark spots.
  • Our skin produces natural oils that promote moisture. These oils will become less occurrent as age continues, making your skin more dry.
  • Collagen degradation
  • You may bruise more easily

Why CBD and Sodium Hyaluronate?

What about CBD and sodium hyaluronate? Is there a connection between the two that makes for a powerful anti-aging concoction? Yes! 

CBD is a plant derived ingredient found in the cannabis sativa family. CBD is a relatively high costing ingredient because of its phenomenal healing characteristics. Not only does CBD have discomfort relieving qualities, but also anti-stress characteristics.

The aging process is set in motion by our DNA’s loss of telomeres. These protective casings found at the end of your DNA strand can break off through chronic stress. When the telomeres becomes too small, the cell dies or becomes pro-inflammatory, setting up the process of aging [16] [17].

CBD is a healthy anti-stress plant option the earth and chemistry has given mankind. It has a very calming nature that many find appealing and beneficial for relieving anxiousness.

Used Sources:

[1] [8] Papakonstantinou, Eleni, et al. “Hyaluronic Acid: A Key Molecule in Skin Aging.” Dermato-Endocrinology, Landes Bioscience, 1 July 2012, 

[2] Franzino, April. “Humectants Are in Every Single Lotion You Use – Here’s What You Need to Know About Them.” Good Housekeeping, Good Housekeeping, 13 Mar. 2020, www.goodhousekeeping.com/beauty/anti-aging/a31156276/what-are-humectants-skincare/.

[3] Casale, Jarett. “Biochemistry, Glycosaminoglycans.” StatPearls [Internet]., U.S. National Library of Medicine, 10 July 2020, www.ncbi.nlm.nih.gov/books/NBK544295/.

[4] Anne Marie Helmenstine, Ph.D. “Hygoscopic vs. Hydroscopic.” ThoughtCo, www.thoughtco.com/definition-of-hygroscopic-605230.

[5] [6] Veterinarni Medicina, 53, 2008 (8): 397–411 

[7] The Water in You: Water and the Human Body, www.usgs.gov/special-topic/water-science-school/science/water-you-water-and-human-body?qt-science_center_objects=0#qt-science_center_objects.

[9] “Sodium Hyaluronate Injection Uses, Side Effects & Warnings.” Drugs.com, www.drugs.com/mtm/sodium-hyaluronate-injection.html#uses.

[10] “Osteoarthritis – What You Need to Know.” Drugs.com, www.drugs.com/cg/osteoarthritis.html.

[11] “Acne.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 12 Sept. 2020, www.mayoclinic.org/diseases-conditions/acne/symptoms-causes/syc-20368047.

[12] Michelle, et al. “Skincare Chemistry: How to Pick out Humectants.” Lab Muffin Beauty Science, 3 Jan. 2019, labmuffin.com/skincare-chemistry-which-ingredients-are-humectants/.

[13] Robin, Marci. “Your Hot Showers May Be the Reason Why Your Skin Is Suffering.” Allure, Allure, 16 Jan. 2020, www.allure.com/story/why-hot-showers-are-bad-for-skin.

[14] “Aging: What to Expect.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 19 Nov. 2020, www.mayoclinic.org/healthy-lifestyle/healthy-aging/in-depth/aging/art-20046070.

[15] “How Much Water Do You Need to Stay Healthy?” Mayo Clinic, Mayo Foundation for Medical Education and Research, 14 Oct. 2020, www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/water/art-20044256#:~:text=The U.S. National Academies of,fluids a day for women.

[16] Publishing, Harvard Health. “Ask the Doctor: Does Stress Make Us Age Faster?” Harvard Health, www.health.harvard.edu/staying-healthy/does-stress-make-us-age-faster.

[17] Lu, Stacy. “How Chronic Stress Is Harming Our DNA.” Monitor on Psychology, American Psychological Association, Oct. 2014, www.apa.org/monitor/2014/10/chronic-stress.

[18] “SKIN ANATOMY & PHYSIOLOGY.” SkinCeuticals, www.skinceuticals.com/skin_explained_understanding_skin_animation.html.

[19] Schneider, Jamie. “Dehydrated vs. Dry Skin: Yes, They’re Different & Here’s What You Need To Know.” Mindbodygreen, Mindbodygreen, 29 Jan. 2020, www.mindbodygreen.com/articles/dehydrated-vs-dry-skin-heres-how-to-tell-difference.

[20] Duncan, Allison. “Here’s How to Tell If Your Skin Is Dry or Dehydrated.” Allure, www.allure.com/story/dry-vs-dehydrated-skin-whats-the-difference.